Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2, and RAD51C Status

Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2, and RAD51C Status

We evaluated homologous recombination deficient (HRD) phenotypes in epithelial ovarian cancer (EOC) considering BRCA1, BRCA2, and RAD51C in a large well-annotated patient set. We evaluated EOC patients for germline deleterious mutations (n = 899), somatic mutations (n = 279) and epigenetic alteratio...

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Bibliographic Details
Main Authors: Cunningham, J. M., Cicek, M. S., Larson, N. B., Davila, J., Wang, C., Larson, M. C., Song, H., Dicks, E. M., Harrington, P., Wick, M., Winterhoff, B. J., Hamidi, H., Konecny, G. E., Chien, J., Bibikova, M., Fan, J.-B., Kalli, K. R., Lindor, N. M., Fridley, B. L., Pharoah, P. P. D., Goode, E. L.
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168524/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168524/

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