Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion

Purpose. The outcome of recanalization in patients with chronic symptomatic intracranial vertebral artery (ICVA) total occlusion is poor. This paper reports the technical feasibility and long-term outcome of ICVA stenting in patients with chronic symptomatic total occlusion. Methods. Retrospective...

Full description

Bibliographic Details
Main Authors: Xu, Ziqi, Ma, Ning, Mo, Dapeng, Wong, Edward Ho chung, Gao, Feng, Jiao, Liqun, Miao, Zhongrong
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168236/
id pubmed-4168236
recordtype oai_dc
spelling pubmed-41682362014-09-28 Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion Xu, Ziqi Ma, Ning Mo, Dapeng Wong, Edward Ho chung Gao, Feng Jiao, Liqun Miao, Zhongrong Clinical Study Purpose. The outcome of recanalization in patients with chronic symptomatic intracranial vertebral artery (ICVA) total occlusion is poor. This paper reports the technical feasibility and long-term outcome of ICVA stenting in patients with chronic symptomatic total occlusion. Methods. Retrospective review of our prospectively maintained intracranial intervention database to identify patients with symptomatic total occlusion of ICVA with revascularization attempted >1 month after index ischemic event. Results. Eight patients (mean age 58 years) were identified. One had stroke and 7 had recurrent transient ischemic attacks. Four had bilateral ICVA total occlusion and 4 had unilateral ICVA total occlusion with severe stenosis contralaterally. Seven of 8 patients underwent endovascular recanalization, which was achieved in 6. Periprocedural complications included cerebellum hemorrhage, arterial dissection, perforation, and subacute in-stent thrombosis which occurred in 3 patients. One patient died of cerebellum hemorrhage. The other patients improved clinically after endovascular therapy. Conclusions. Stent-supported recanalization of ICVA total occlusion is technically feasible, and may become a viable treatment option in selected patients. Hindawi Publishing Corporation 2014 2014-09-03 /pmc/articles/PMC4168236/ /pubmed/25276423 http://dx.doi.org/10.1155/2014/949585 Text en Copyright © 2014 Ziqi Xu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Xu, Ziqi
Ma, Ning
Mo, Dapeng
Wong, Edward Ho chung
Gao, Feng
Jiao, Liqun
Miao, Zhongrong
spellingShingle Xu, Ziqi
Ma, Ning
Mo, Dapeng
Wong, Edward Ho chung
Gao, Feng
Jiao, Liqun
Miao, Zhongrong
Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
author_facet Xu, Ziqi
Ma, Ning
Mo, Dapeng
Wong, Edward Ho chung
Gao, Feng
Jiao, Liqun
Miao, Zhongrong
author_sort Xu, Ziqi
title Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
title_short Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
title_full Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
title_fullStr Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
title_full_unstemmed Endovascular Recanalization for Chronic Symptomatic Intracranial Vertebral Artery Total Occlusion
title_sort endovascular recanalization for chronic symptomatic intracranial vertebral artery total occlusion
description Purpose. The outcome of recanalization in patients with chronic symptomatic intracranial vertebral artery (ICVA) total occlusion is poor. This paper reports the technical feasibility and long-term outcome of ICVA stenting in patients with chronic symptomatic total occlusion. Methods. Retrospective review of our prospectively maintained intracranial intervention database to identify patients with symptomatic total occlusion of ICVA with revascularization attempted >1 month after index ischemic event. Results. Eight patients (mean age 58 years) were identified. One had stroke and 7 had recurrent transient ischemic attacks. Four had bilateral ICVA total occlusion and 4 had unilateral ICVA total occlusion with severe stenosis contralaterally. Seven of 8 patients underwent endovascular recanalization, which was achieved in 6. Periprocedural complications included cerebellum hemorrhage, arterial dissection, perforation, and subacute in-stent thrombosis which occurred in 3 patients. One patient died of cerebellum hemorrhage. The other patients improved clinically after endovascular therapy. Conclusions. Stent-supported recanalization of ICVA total occlusion is technically feasible, and may become a viable treatment option in selected patients.
publisher Hindawi Publishing Corporation
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168236/
_version_ 1613135176764751872