Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response
The brain, in particular the hypothalamus, plays a role in regulating glucose homeostasis; however, it remains unclear if the brain is causally involved in diabetic development. Here, we identified that hypothalamic TGF-β is excessive under conditions of not only obesity but aging, which are two gen...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167789/ |