Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

In this study, Proitsi and colleagues use a Mendelian randomization approach to dissect the causal nature of the association between circulating lipid levels and late onset Alzheimer's Disease (LOAD) and find that genetic predisposition to increased plasma cholesterol and triglyceride lipid lev...

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Bibliographic Details
Main Authors: Proitsi, Petroula, Lupton, Michelle K., Velayudhan, Latha, Newhouse, Stephen, Fogh, Isabella, Tsolaki, Magda, Daniilidou, Makrina, Pritchard, Megan, Kloszewska, Iwona, Soininen, Hilkka, Mecocci, Patrizia, Vellas, Bruno, Williams, Julie, Stewart, Robert, Sham, Pak, Lovestone, Simon, Powell, John F.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165594/