mTORC1 Is Essential for Early Steps during Schwann Cell Differentiation of Amniotic Fluid Stem Cells and Regulates Lipogenic Gene Expression

Schwann cell development is hallmarked by the induction of a lipogenic profile. Here we used amniotic fluid stem (AFS) cells and focused on the mechanisms occurring during early steps of differentiation along the Schwann cell lineage. Therefore, we initiated Schwann cell differentiation in AFS cells...

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Bibliographic Details
Main Authors: Preitschopf, Andrea, Li, Kongzhao, Schörghofer, David, Kinslechner, Katharina, Schütz, Birgit, Thi Thanh Pham, Ha, Rosner, Margit, Joo, Gabor Jozsef, Röhrl, Clemens, Weichhart, Thomas, Stangl, Herbert, Lubec, Gert, Hengstschläger, Markus, Mikula, Mario
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164523/