Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16
Tissue-specific gene expression is regulated by epigenetic modification involving trans-acting factors. Here, we identified that the human MAGEB16 gene and its mouse homolog, Mageb16, are only expressed in the testis. To investigate the mechanism governing their expression, the promoter methylation...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Society for Biochemistry and Molecular Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163901/ |