SPONTANEOUS TRANSMEMBRANE HELIX INSERTION THERMODYNAMICALLY MIMICS TRANSLOCON-GUIDED INSERTION
The favorable transfer free energy for a transmembrane (TM) α-helix between the aqueous phase and lipid bilayer underlies the stability of membrane proteins. However, the connection between the energetics and process of membrane protein assembly by the Sec61/SecY translocon complex in vivo is not cl...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161982/ |