Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport

The subcellular distribution of yeast β-importins inverts upon acute glucose deprivation, likely due to collapse of the RanGTP nuclear–cytoplasmic gradient. This redistribution of β-importins likely results in rapid widespread alterations of the traffic of macromolecules between the nucleus and cyto...

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Bibliographic Details
Main Authors: Huang, Hsiao-Yun, Hopper, Anita K.
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161518/