RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

RBFOX1 Cooperates with MBNL1 to Control Splicing in Muscle, Including Events Altered in Myotonic Dystrophy Type 1

With the goal of identifying splicing alterations in myotonic dystrophy 1 (DM1) tissues that may yield insights into targets or mechanisms, we have surveyed mis-splicing events in three systems using a RT-PCR screening and validation platform. First, a transgenic mouse model expressing CUG-repeats i...

Full description

Bibliographic Details
Main Authors: Klinck, Roscoe, Fourrier, Angélique, Thibault, Philippe, Toutant, Johanne, Durand, Mathieu, Lapointe, Elvy, Caillet-Boudin, Marie-Laure, Sergeant, Nicolas, Gourdon, Geneviève, Meola, Giovanni, Furling, Denis, Puymirat, Jack, Chabot, Benoit
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161394/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161394/

Similar Items