Mouse liver repopulation with hepatocytes generated from human fibroblasts

Human induced pluripotent stem cells (iPSCs) promise to revolutionize research and therapy of liver diseases by providing a source of hepatocytes for autologous cell therapy and disease modeling. However, despite progress in advancing the differentiation of iPSCs into hepatocytes (iPSC-Heps) in vitr...

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Bibliographic Details
Main Authors: Zhu, Saiyong, Rezvani, Milad, Harbell, Jack, Mattis, Aras N., Wolfe, Alan R., Benet, Leslie Z., Willenbring, Holger, Ding, Sheng
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161230/