Drug-Like Protein–Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology
Fundamental processes in living cells are largely controlled by macromolecular interactions and among them, protein–protein interactions (PPIs) have a critical role while their dysregulations can contribute to the pathogenesis of numerous diseases. Although PPIs were considered as attractive pharmac...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160817/ |