G protein coupled receptor signaling complexes in live cells
Classical models of receptor (GPCR) and G protein (Gαβγ) signaling based on biochemical studies have proposed that receptor stimulation results in G protein activation (Gα-GTP) and dissociation of the heterotrimer (Gα-GTP + Gβγ) to regulate downstream signaling events. Unclear is whether or not ther...
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| Format: | Online |
| Language: | English |
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Landes Bioscience
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160338/ |