Biofragments: An Approach towards Predicting Protein Function Using Biologically Related Fragments and its Application to Mycobacterium tuberculosis CYP126

We present a novel fragment-based approach that tackles some of the challenges for chemical biology of predicting protein function. The general approach, which we have termed biofragments, comprises two key stages. First, a biologically relevant fragment library (biofragment library) can be designed...

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Bibliographic Details
Main Authors: Hudson, Sean A, Mashalidis, Ellene H, Bender, Andreas, McLean, Kirsty J, Munro, Andrew W, Abell, Chris
Format: Online
Language:English
Published: WILEY-VCH Verlag 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159592/