Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model

Calbindin-D28k (CB), one of the major calcium-binding and buffering proteins, has a critical role in preventing a neuronal death as well as maintaining calcium homeostasis. Although marked reductions of CB expression have been observed in the brains of mice and humans with Alzheimer disease (AD), it...

Full description

Bibliographic Details
Main Authors: Kook, S-Y, Jeong, H, Kang, M J, Park, R, Shin, H J, Han, S-H, Son, S M, Song, H, Baik, S H, Moon, M, Yi, E C, Hwang, D, Mook-Jung, I
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158683/