Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease

Erdheim–Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The 99mtechnetium-methylene diphosphonate (99mTc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other causes...

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Main Authors: Mukherjee, Anirban, Damle, Nishikant, Bal, Chandrasekhar, Arora, Arundeep, Singhal, Abhinav, Tripathi, Madhavi, Peepre, Karan
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157192/
id pubmed-4157192
recordtype oai_dc
spelling pubmed-41571922014-09-10 Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease Mukherjee, Anirban Damle, Nishikant Bal, Chandrasekhar Arora, Arundeep Singhal, Abhinav Tripathi, Madhavi Peepre, Karan Case Report Erdheim–Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The 99mtechnetium-methylene diphosphonate (99mTc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other causes of bony pain. Also a scintigraphic pattern consistent with ECD should alert the physician to evaluate the patient for visceral sites of involvement using fludeoxyglucose positron emission tomography/computed tomography (FDG PET/CT), as this is known to be fatal at times. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4157192/ /pubmed/25210284 http://dx.doi.org/10.4103/0972-3919.136575 Text en Copyright: © Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Mukherjee, Anirban
Damle, Nishikant
Bal, Chandrasekhar
Arora, Arundeep
Singhal, Abhinav
Tripathi, Madhavi
Peepre, Karan
spellingShingle Mukherjee, Anirban
Damle, Nishikant
Bal, Chandrasekhar
Arora, Arundeep
Singhal, Abhinav
Tripathi, Madhavi
Peepre, Karan
Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
author_facet Mukherjee, Anirban
Damle, Nishikant
Bal, Chandrasekhar
Arora, Arundeep
Singhal, Abhinav
Tripathi, Madhavi
Peepre, Karan
author_sort Mukherjee, Anirban
title Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
title_short Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
title_full Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
title_fullStr Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
title_full_unstemmed Role of 99mTc-MDP bone scan in the diagnosis of Erdheim–Chester disease
title_sort role of 99mtc-mdp bone scan in the diagnosis of erdheim–chester disease
description Erdheim–Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The 99mtechnetium-methylene diphosphonate (99mTc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other causes of bony pain. Also a scintigraphic pattern consistent with ECD should alert the physician to evaluate the patient for visceral sites of involvement using fludeoxyglucose positron emission tomography/computed tomography (FDG PET/CT), as this is known to be fatal at times.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157192/
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