Rice ORMDL Controls Sphingolipid Homeostasis Affecting Fertility Resulting from Abnormal Pollen Development

The orosomucoids (ORM) are ER-resisdent polypeptides encoded by ORM and ORMDL (ORM-like) genes. In humans, ORMDL3 was reported as genetic risk factor associated to asthma. In yeast, ORM proteins act as negative regulators of sphingolipid synthesis. Sphingolipids are important molecules regulating se...

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Bibliographic Details
Main Authors: Chueasiri, Chutharat, Chunthong, Ketsuwan, Pitnjam, Keasinee, Chakhonkaen, Sriprapai, Sangarwut, Numphet, Sangsawang, Kanidta, Suksangpanomrung, Malinee, Michaelson, Louise V., Napier, Johnathan A., Muangprom, Amorntip
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156325/