Whole-genome sequencing to control antimicrobial resistance

•Owing to improvements in sequencing technologies, microbial whole-genome sequencing (WGS) has emerged as a central tool to control antibiotic resistance.•WGS has been used to develop novel antibiotics and diagnostic tests.•WGS has been key to surveillance and the study of the emergence of antibioti...

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Main Authors: Köser, Claudio U., Ellington, Matthew J., Peacock, Sharon J.
Format: Online
Language:English
Published: Elsevier Trends Journals 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156311/
id pubmed-4156311
recordtype oai_dc
spelling pubmed-41563112014-09-06 Whole-genome sequencing to control antimicrobial resistance Köser, Claudio U. Ellington, Matthew J. Peacock, Sharon J. Review •Owing to improvements in sequencing technologies, microbial whole-genome sequencing (WGS) has emerged as a central tool to control antibiotic resistance.•WGS has been used to develop novel antibiotics and diagnostic tests.•WGS has been key to surveillance and the study of the emergence of antibiotic resistance.•Rapid WGS has the potential to be used as a tool for infection control in the clinic and, in some cases, as a primary diagnostic tool to detect resistance. Elsevier Trends Journals 2014-09 /pmc/articles/PMC4156311/ /pubmed/25096945 http://dx.doi.org/10.1016/j.tig.2014.07.003 Text en © 2014 The Authors
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Köser, Claudio U.
Ellington, Matthew J.
Peacock, Sharon J.
spellingShingle Köser, Claudio U.
Ellington, Matthew J.
Peacock, Sharon J.
Whole-genome sequencing to control antimicrobial resistance
author_facet Köser, Claudio U.
Ellington, Matthew J.
Peacock, Sharon J.
author_sort Köser, Claudio U.
title Whole-genome sequencing to control antimicrobial resistance
title_short Whole-genome sequencing to control antimicrobial resistance
title_full Whole-genome sequencing to control antimicrobial resistance
title_fullStr Whole-genome sequencing to control antimicrobial resistance
title_full_unstemmed Whole-genome sequencing to control antimicrobial resistance
title_sort whole-genome sequencing to control antimicrobial resistance
description •Owing to improvements in sequencing technologies, microbial whole-genome sequencing (WGS) has emerged as a central tool to control antibiotic resistance.•WGS has been used to develop novel antibiotics and diagnostic tests.•WGS has been key to surveillance and the study of the emergence of antibiotic resistance.•Rapid WGS has the potential to be used as a tool for infection control in the clinic and, in some cases, as a primary diagnostic tool to detect resistance.
publisher Elsevier Trends Journals
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156311/
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