An atomic model of brome mosaic virus using direct electron detection and real-space optimization
Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisition, image pro...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155512/ |