Towards efficient cancer immunotherapy: advances in developing artificial antigen-presenting cells

•Active immunotherapy is promising for the development of potent cancer therapeutics.•Various types of artificial antigen-presenting cells (aAPCs) may be used as ‘off-the-shelf’ products to induce antigen-specific T cell activation both ex vivo and in vivo.•Size, shape, cytokine delivery mechanism,...

Full description

Bibliographic Details
Main Authors: Eggermont, Loek J., Paulis, Leonie E., Tel, Jurjen, Figdor, Carl G.
Format: Online
Language:English
Published: Elsevier Science Publishers 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154451/