Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells

Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and is often resistant to standard chemotherapeutic options, contributing to extremely poor disease outcomes. Members of the nuclear receptor superfamily carry out essential biological functions such as hormone signaling and are su...

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Bibliographic Details
Main Authors: Candelaria, Nicholes R., Addanki, Sridevi, Zheng, Jine, Nguyen-Vu, Trang, Karaboga, Husna, Dey, Prasenjit, Gabbi, Chiara, Vedin, Lise-Lotte, Liu, Ka, Wu, Wanfu, Jonsson, Philip K., Lin, Jean Z., Su, Fei, Bollu, Lakshmi Reddy, Hodges, Sally E., McElhany, Amy L., Issazadeh, Mehdi A., Fisher, William E., Ittmann, Michael M., Steffensen, Knut R., Gustafsson, Jan-Åke, Lin, Chin-Yo
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153644/