TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)
After hepatitis virus infection, plasma transforming growth factor (TGF)-β increases in either the acute or chronic inflammatory microenvironment. Although TGF-β is upregulated in patients with hepatocellular carcinoma, it is one of the most potent growth inhibitors for hepatocytes. This cytokine al...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151811/ |