TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)

After hepatitis virus infection, plasma transforming growth factor (TGF)-β increases in either the acute or chronic inflammatory microenvironment. Although TGF-β is upregulated in patients with hepatocellular carcinoma, it is one of the most potent growth inhibitors for hepatocytes. This cytokine al...

Full description

Bibliographic Details
Main Authors: YOSHIDA, KATSUNORI, MURATA, MIKI, YAMAGUCHI, TAKASHI, ZAKI, KOICHI MATSU
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151811/