A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model
A therapeutic vaccine against minimal residual cancer cells is needed for the treatment of patients with colorectal cancer. Several gene therapy studies have revealed that the combination of a suicide gene and cytokine gene might induce effective antitumor immunity. In this study, we constructed an...
Main Authors: | , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151806/ |