Sustained Release of Prostaglandin E2 in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca2+-Mobilization

The nucleotide uridine trisphosphate (UTP) released to the extracellular milieu acts as a signaling molecule via activation of specific pyrimidine receptors (P2Y). P2Y receptors are G protein-coupled receptors expressed in many cell types. These receptors mediate several cell responses and they are...

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Bibliographic Details
Main Authors: Pimentel-Santillana, María, Través, Paqui G., Pérez-Sen, Raquel, Delicado, Esmerilda G., Martín-Sanz, Paloma, Miras-Portugal, María Teresa, Boscá, Lisardo
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151624/