Predicting QTc Prolongation in Man From Only In Vitro Data
Mishra et al.1 in their article “Interaction between domperidone and ketoconazole: toward prediction of consequent QTc prolongation using purely in vitro information” describe the use of physiologically based pharmacokinetic (PBPK) modeling and pharmacodynamic models of cardiac repolarization to pre...
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| Format: | Online |
| Language: | English |
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Nature Publishing Group
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150928/ |