Prion propagation can occur in a prokaryote and requires the ClpB chaperone
Prions are self-propagating protein aggregates that are characteristically transmissible. In mammals, the PrP protein can form a prion that causes the fatal transmissible spongiform encephalopathies. Prions have also been uncovered in fungi, where they act as heritable, protein-based genetic element...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150125/ |