Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms

Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms

Detailed analysis of disease-affected tissue provides insight into molecular mechanisms contributing to pathogenesis. Substantia nigra, striatum, and cortex are functionally connected with increasing degrees of alpha-synuclein pathology in Parkinson's disease. We undertook functional and causal...

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Bibliographic Details
Main Authors: Riley, Brigit E., Gardai, Shyra J., Emig-Agius, Dorothea, Bessarabova, Marina, Ivliev, Alexander E., Schüle, Birgit, Alexander, Jeff, Wallace, William, Halliday, Glenda M., Langston, J. William, Braxton, Scott, Yednock, Ted, Shaler, Thomas, Johnston, Jennifer A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149353/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149353/

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