Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/S-phase cell cycle arrest and apoptosis through caspase/cyclin-CDK pathways

The present study compared the effect of resveratrol on HCT116 and Caco-2 human colon cancer cells. Annexin V/propidium iodide staining, MTT assay and western blot analysis revealed that resveratrol induced cycle arrest in the two cell lines, which was evidenced by cell cycle analysis and changes in...

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Bibliographic Details
Main Authors: LIU, BIN, ZHOU, ZHONGYOU, ZHOU, WEI, LIU, JIE, ZHANG, QINGYU, XIA, JUAN, LIU, JUNTAO, CHEN, NIANPING, LI, MINGYI, ZHU, RUNZHI
Format: Online
Language:English
Published: D.A. Spandidos 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148380/