The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions
Cilia and flagella are assembled by intraflagellar transport (IFT). The protist Trypanosoma brucei is used to investigate retrograde IFT. A model is proposed by which the IFT dynein particle is assembled in the cytoplasm, transferred to the base of the flagellum, and associated with the IFT machiner...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148251/ |