Mechanisms of HIV Protein Degradation into Epitopes: Implications for Vaccine Design
The degradation of HIV-derived proteins into epitopes displayed by MHC-I or MHC-II are the first events leading to the priming of HIV-specific immune responses and to the recognition of infected cells. Despite a wealth of information about peptidases involved in protein degradation, our knowledge of...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147695/ |