Mechanisms of HIV Protein Degradation into Epitopes: Implications for Vaccine Design

The degradation of HIV-derived proteins into epitopes displayed by MHC-I or MHC-II are the first events leading to the priming of HIV-specific immune responses and to the recognition of infected cells. Despite a wealth of information about peptidases involved in protein degradation, our knowledge of...

Full description

Bibliographic Details
Main Authors: Rucevic, Marijana, Boucau, Julie, Dinter, Jens, Kourjian, Georgio, Le Gall, Sylvie
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147695/