Protective Antigen-Specific Memory B Cells Persist Years after Anthrax Vaccination and Correlate with Humoral Immunity

Anthrax Vaccine Adsorbed (AVA) generates short-lived protective antigen (PA) specific IgG that correlates with in vitro toxin neutralization and protection from Bacillus anthracis challenge. Animal studies suggest that when PA-specific IgG has waned, survival after spore challenge correlates with an...

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Bibliographic Details
Main Authors: Garman, Lori, Smith, Kenneth, Farris, A. Darise, Nelson, Michael R., Engler, Renata J. M., James, Judith A.
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147590/