XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is a neoplasia characterized by the rapid expansion of immature myeloid blasts in the bone marrow, and marked by poor prognosis and frequent relapse. As such, new therapeutic approaches are required for remission induction and prevention of relapse. Due to the higher che...

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Bibliographic Details
Main Authors: Moreno-Martínez, Daniel, Nomdedeu, Meritxell, Lara-Castillo, María Carmen, Etxabe, Amaia, Pratcorona, Marta, Tesi, Niccolò, Díaz-Beyá, Marina, Rozman, María, Montserrat, Emili, Urbano-Ispizua, Álvaro, Esteve, Jordi, Risueño, Ruth M.
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147327/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147327/

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