Embryonic GABAB Receptor Blockade Alters Cell Migration, Adult Hypothalamic Structure, and Anxiety- and Depression-Like Behaviors Sex Specifically in Mice

Embryonic GABAB Receptor Blockade Alters Cell Migration, Adult Hypothalamic Structure, and Anxiety- and Depression-Like Behaviors Sex Specifically in Mice

Neurons of the paraventricular nucleus of the hypothalamus (PVN) regulate the hypothalamic- pituitary-adrenal (HPA) axis and the autonomic nervous system. Females lacking functional GABAB receptors because of a genetic disruption of the R1 subunit have altered cellular characteristics in and around...

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Bibliographic Details
Main Authors: Stratton, Matthew S., Staros, Michelle, Budefeld, Tomaz, Searcy, Brian T., Nash, Connor, Eitel, Chad, Carbone, David, Handa, Robert J., Majdic, Gregor, Tobet, Stuart A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146593/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146593/

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