Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment1234

The bone microenvironment (BME) is the main hub of all skeletal related pathological events in osteosarcoma leading to tumor induced bone destruction, and decreasing overall bone quality and bone strength. The role of extra-cellular membrane vesicles (EMVs) as mediators of intercellular communicatio...

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Bibliographic Details
Main Authors: Garimella, Rama, Washington, Laurie, Isaacson, Janalee, Vallejo, Julian, Spence, Madoka, Tawfik, Ossama, Rowe, Peter, Brotto, Marco, Perez, Raymond
Format: Online
Language:English
Published: Neoplasia Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145399/