Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment1234
The bone microenvironment (BME) is the main hub of all skeletal related pathological events in osteosarcoma leading to tumor induced bone destruction, and decreasing overall bone quality and bone strength. The role of extra-cellular membrane vesicles (EMVs) as mediators of intercellular communicatio...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Neoplasia Press
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145399/ |