Uptake of [18F] EF5 as a Tracer for Hypoxic and Aggressive Phenotype in Experimental Head and Neck Squamous Cell Carcinoma1

PURPOSE: This study aims to investigate whether the uptake of 2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)-acetamide ([18F]EF5) and 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) is associated with a hypoxia-driven adverse phenotype in head and neck squamous cell carcinoma cell lines and...

Full description

Bibliographic Details
Main Authors: Silén, Jonna, Högel, Heidi, Kivinen, Katri, Silvoniemi, Antti, Forsback, Sarita, Löyttyniemi, Eliisa, Solin, Olof, Grénman, Reidar, Minn, Heikki, Jaakkola, Panu M., Grönroos, Tove J.
Format: Online
Language:English
Published: Neoplasia Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145394/