Single molecule analysis of transcription factor binding at transcription sites in live cells

Although numerous live-cell measurements have shown that transcription factors bind chromatin transiently, no measurements of transient binding have been reported at the endogenous response elements (REs) where transcription is normally induced. Here we show that at endogenous REs, the transcription...

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Bibliographic Details
Main Authors: Morisaki, Tatsuya, Müller, Waltraud G., Golob, Nicole, Mazza, Davide, McNally, James G.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144071/