Detecting association of rare and common variants by testing an optimally weighted combination of variants with longitudinal data

Increasing evidence shows that complex diseases are caused by both common and rare variants. Recently, several statistical methods for detecting associations of rare variants have been developed, including the test for testing the effect of an optimally weighted combination of variants (TOW) develop...

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Bibliographic Details
Main Authors: Wang, Shuaicheng, Fang, Shurong, Sha, Qiuying, Zhang, Shuanglin
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143720/