Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data

We apply a family-based extension of the sequence kernel association test (SKAT) to 93 trios extracted from the 20 pedigrees in the Genetic Analysis Workshop 18 simulated data. Each extracted trio includes a unique set of parents to ensure conditionally independent trios are sampled. We compare the...

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Bibliographic Details
Main Authors: Huang, Jing, Chen, Yong, Swartz, Michael D, Ionita-Laza, Iuliana
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143708/