Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data
We apply a family-based extension of the sequence kernel association test (SKAT) to 93 trios extracted from the 20 pedigrees in the Genetic Analysis Workshop 18 simulated data. Each extracted trio includes a unique set of parents to ensure conditionally independent trios are sampled. We compare the...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143708/ |