Integrated statistical and pathway approach to next-generation sequencing analysis: a family-based study of hypertension

Genome wide association studies (GWAS) have been used to search for associations between genetic variants and a phenotypic trait of interest. New technologies, such as next-generation sequencing, hold the potential to revolutionize GWAS. However, millions of polymorphisms are identified with next-ge...

Full description

Bibliographic Details
Main Authors: Edwards, Jeremy S, Atlas, Susan R, Wilson, Susan M, Cooper, Candice F, Luo, Li, Stidley, Christine A
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143684/