Accounting for relatedness in family-based association studies: application to Genetic Analysis Workshop 18 data

In the last few years, a bewildering variety of methods/software packages that use linear mixed models to account for sample relatedness on the basis of genome-wide genomic information have been proposed. We compared these approaches as implemented in the programs EMMAX, FaST-LMM, Gemma, and GenABEL...

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Bibliographic Details
Main Authors: Eu-ahsunthornwattana, Jakris, Howey, Richard AJ, Cordell, Heather J
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143672/