Fast genome-wide pedigree quantitative trait loci analysis using MENDEL

The linkage era left a rich legacy of pedigree samples that can be used for modern genome-wide association sequencing (GWAS) or next-generation sequencing (NGS) studies. Family designs are naturally equipped to detect rare variants, control for population stratification, and facilitate the study of...

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Bibliographic Details
Main Authors: Zhou, Hua, Zhou, Jin, Sobel, Eric M, Lange, Kenneth
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143629/