Fast genome-wide pedigree quantitative trait loci analysis using MENDEL
The linkage era left a rich legacy of pedigree samples that can be used for modern genome-wide association sequencing (GWAS) or next-generation sequencing (NGS) studies. Family designs are naturally equipped to detect rare variants, control for population stratification, and facilitate the study of...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143629/ |