RNA sequencing: from tag-based profiling to resolving complete transcript structure

Technological advances in the sequencing field support in-depth characterization of the transcriptome. Here, we review genome-wide RNA sequencing methods used to investigate specific aspects of gene expression and its regulation, from transcription to RNA processing and translation. We discuss tag-b...

Full description

Bibliographic Details
Main Authors: de Klerk, Eleonora, den Dunnen, Johan T., ‘t Hoen, Peter A. C.
Format: Online
Language:English
Published: Springer Basel 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143603/