Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose

Pectin is a structural heteropolysaccharide of the primary cell walls of plants and as such is a significant fraction of agricultural waste residues that is currently insufficiently used. Its main component, D-galacturonic acid, is an attractive substrate for bioconversion. The complete metabolic pa...

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Main Authors: Sloothaak, Jasper, Schilders, Mike, Schaap, Peter J, de Graaff, Leo H
Format: Online
Language:English
Published: Springer 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143577/
id pubmed-4143577
recordtype oai_dc
spelling pubmed-41435772014-08-29 Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose Sloothaak, Jasper Schilders, Mike Schaap, Peter J de Graaff, Leo H Original Article Pectin is a structural heteropolysaccharide of the primary cell walls of plants and as such is a significant fraction of agricultural waste residues that is currently insufficiently used. Its main component, D-galacturonic acid, is an attractive substrate for bioconversion. The complete metabolic pathway is present in the genome of Aspergillus niger, that is used in this study. The objective was to identify the D-galacturonic acid transporter in A. niger and to use this transporter to study D-galacturonic acid metabolism. Springer 2014-08-23 /pmc/articles/PMC4143577/ /pubmed/25177540 http://dx.doi.org/10.1186/s13568-014-0066-3 Text en Copyright © 2014 Sloothaak et al.; licensee Springer http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Sloothaak, Jasper
Schilders, Mike
Schaap, Peter J
de Graaff, Leo H
spellingShingle Sloothaak, Jasper
Schilders, Mike
Schaap, Peter J
de Graaff, Leo H
Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
author_facet Sloothaak, Jasper
Schilders, Mike
Schaap, Peter J
de Graaff, Leo H
author_sort Sloothaak, Jasper
title Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
title_short Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
title_full Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
title_fullStr Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
title_full_unstemmed Overexpression of the Aspergillus niger GatA transporter leads to preferential use of D-galacturonic acid over D-xylose
title_sort overexpression of the aspergillus niger gata transporter leads to preferential use of d-galacturonic acid over d-xylose
description Pectin is a structural heteropolysaccharide of the primary cell walls of plants and as such is a significant fraction of agricultural waste residues that is currently insufficiently used. Its main component, D-galacturonic acid, is an attractive substrate for bioconversion. The complete metabolic pathway is present in the genome of Aspergillus niger, that is used in this study. The objective was to identify the D-galacturonic acid transporter in A. niger and to use this transporter to study D-galacturonic acid metabolism.
publisher Springer
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143577/
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