A role for nuclear envelope–bridging complexes in homology-directed repair
Persistent double-strand DNA breaks (DSBs) are recruited to the nuclear periphery, where they induce formation of associated nuclear envelope–spanning LINC complexes made up of the SUN protein Sad1 and the KASH protein Kms1. The LINC complex couples DSBs within the nucleus to cytoplasmic microtubule...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142617/ |