Mitogen-Activated Protein Kinase Phosphatase 3 (MKP-3)–Deficient Mice Are Resistant to Diet-Induced Obesity

Mitogen-activated protein kinase phosphatase 3 (MKP-3) is a negative regulator of extracellular signal–related kinase signaling. Our laboratory recently demonstrated that MKP-3 plays an important role in obesity-related hyperglycemia by promoting hepatic glucose output. This study shows that MKP-3 d...

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Bibliographic Details
Main Authors: Feng, Bin, Jiao, Ping, Helou, Ynes, Li, Yujie, He, Qin, Walters, Matthew S., Salomon, Arthur, Xu, Haiyan
Format: Online
Language:English
Published: American Diabetes Association 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141371/