Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

The presence of multiple (5–100) colorectal adenomas suggests an inherited predisposition, but the genetic aetiology of this phenotype is undetermined if patients test negative for Mendelian polyposis syndromes such as familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP). We inv...

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Bibliographic Details
Main Authors: Cheng, Timothy H T, Gorman, Maggie, Martin, Lynn, Barclay, Ella, Casey, Graham, Saunders, Brian, Thomas, Huw, Clark, Sue, Tomlinson, Ian
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140766/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140766/

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