Documentation and Localization of Force-mediated Filamin A Domain Perturbations in Moving Cells

Endogenously and externally generated mechanical forces influence diverse cellular activities, a phenomenon defined as mechanotransduction. Deformation of protein domains by application of stress, previously documented to alter macromolecular interactions in vitro, could mediate these effects. We en...

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Bibliographic Details
Main Authors: Nakamura, Fumihiko, Song, Mia, Hartwig, John H., Stossel, Thomas P.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139033/