Neutralizing Antibodies Inhibit HIV-1 Infection of Plasmacytoid Dendritic Cells by an FcγRIIa Independent Mechanism and Do Not Diminish Cytokines Production

Neutralizing Antibodies Inhibit HIV-1 Infection of Plasmacytoid Dendritic Cells by an FcγRIIa Independent Mechanism and Do Not Diminish Cytokines Production

Plasmacytoid dendritic cells (pDC) expressing FcγRIIa are antigen-presenting cells able to link innate and adaptive immunity and producing various cytokines and chemokines. Although highly restricted, they are able to replicate HIV-1. We determined the activity of anti-HIV-1 neutralizing antibodies...

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Bibliographic Details
Main Authors: Lederle, Alexandre, Su, Bin, Holl, Vincent, Penichon, Julien, Schmidt, Sylvie, Decoville, Thomas, Laumond, Géraldine, Moog, Christiane
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135332/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135332/

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