Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Tumor behavior is affected by the tumor microenvironment, composed of cancer-associated fibroblasts (CAFs). Meanwhile, hepatocellular carcinomas (HCC) with fibrous stroma reportedly exhibit aggressive behavior suggestive of tumor-stroma interaction. However, evidence of the crosstalk remains unclear...

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Bibliographic Details
Main Authors: Kim, Gi Jeong, Rhee, Hyungjin, Yoo, Jeong Eun, Ko, Jung Eun, Lee, Jee San, Kim, Hyunki, Choi, Jin Sub, Park, Young Nyun
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134271/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134271/

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