Somatic mutation patterns and compound response in cancers

The use of various cancer cell lines can recapitulate known tumor-associated mutations and genetically define cancer subsets. This approach also enables comparative surveys of associations between cancer mutations and drug responses. Here, we analyzed the effects of ∼40,000 compounds on cancer cell...

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Bibliographic Details
Main Authors: He, Ningning, Kim, Nayoung, Yoon, Sukjoon
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133857/