Egr-1 regulates the transcription of the BRCA1 gene by etoposide

The breast cancer susceptibility gene BRCA1 encodes a nuclear protein, which functions as a tumor suppressor and is involved in gene transcription and DNA repair processes. Many families with inherited breast and ovarian cancers have mutations in the BRCA1 gene. However, only a few studies have repo...

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Bibliographic Details
Main Authors: Shin, Soon Young, Kim, Chang Gun, Lee, Young Han
Format: Online
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133847/